卵巢癌能治好吗？4种治疗与监测方式：机器人手术、HIPEC、尼拉帕利和ctDNA液体活检
卵巢癌治疗能否达到治愈、长期缓解或疾病控制，取决于癌症类型、分期、肿瘤范围、是否发生腹腔或远处转移、手术切除程度、对化疗或靶向治疗的反应，以及患者整体健康状况。
近年来，机器人辅助手术（Robotic Surgery）、腹腔热灌注化疗（HIPEC）、PARP抑制剂尼拉帕利（Niraparib）以及ctDNA液体活检，分别应用于部分患者的手术治疗、腹腔内疾病控制、维持治疗及治疗后监测。
对于部分早期卵巢癌患者，治疗通常以手术为主，并根据病理结果评估是否需要进一步治疗；对于晚期、腹腔转移或复发性卵巢癌，医生可能结合手术、化疗、靶向治疗及其他治疗方式制定个性化方案。
卵巢癌治疗重点摘要
- 卵巢癌能否治愈或长期控制因人而异，需要结合癌症类型、分期、转移范围、治疗反应及整体健康状况综合评估。
- 卵巢癌治疗通常不是单一治疗。 医生可能根据病情组合手术、化疗、靶向治疗及其他治疗方式。
- 早期卵巢癌与晚期、腹腔转移或复发性卵巢癌的治疗策略可能不同。
- 机器人辅助手术可用于部分适合微创手术的早期或局限性妇科肿瘤患者。
- HIPEC腹腔热灌注化疗可在部分适合的晚期卵巢癌患者中，与肿瘤减灭手术结合使用。
- 尼拉帕利（Niraparib）属于PARP抑制剂，可作为部分卵巢癌患者完成含铂化疗后的维持治疗。
- ctDNA液体活检可用于部分患者的分子检测及治疗后监测，但不能单独取代影像、肿瘤标志物及医生评估。
- 无论采用哪种创新治疗方式，都需要由妇科肿瘤专科医生进行完整评估。
Is Ovarian Cancer Curable?
Whether ovarian cancer can be cured does not have a single answer, as treatment outcomes depend on several factors, including the type of cancer cells, the stage of the disease, the location of metastases, the extent of tumour removal during surgery, the response to chemotherapy or targeted therapy, and the patient’s overall health.
For some patients, particularly those diagnosed at an early stage, doctors may be able to develop a treatment plan that offers better disease control. For patients with advanced or recurrent disease, treatment may focus on controlling the disease, relieving symptoms, prolonging remission, and maintaining quality of life.
The most important step is a comprehensive evaluation by a specialist to develop the most appropriate treatment plan for each patient. Patients should not judge their chances of recovery based solely on the stage of the disease or on general information.
Treatment Options for Ovarian Cancer
Treatment for ovarian cancer depends on the type and stage of the disease. Doctors may use a single treatment or a combination of treatments, depending on each patient’s individual needs. Common treatment options include:
- Surgery to remove the tumour or affected tissue.
- Chemotherapy to control or manage cancer cells that may have spread throughout the body.
- HIPEC (hyperthermic intraperitoneal chemotherapy), combined with surgery in some patients, to treat small cancer deposits that have spread within the abdomen.
- Targeted therapy to help control the disease and prolong periods of remission, such as niraparib for some patients after chemotherapy.
Although there are several treatment options for ovarian cancer, the most appropriate treatment cannot be determined by the patient alone. Doctors will consider various factors, including the stage and location of the disease, pathology results, and genetic or molecular testing. After treatment, doctors will continue to monitor the patient’s response and check for any signs of recurrence.
4 Innovative Ovarian Cancer Treatments New Options for Different Stages of the Disease
| Innovation | Main Role | Suitable For | Strengths | Considerations |
| Robotic Surgery | Robot-assisted surgery overcomes many of the limitations of conventional laparoscopic surgery. | It may be suitable for treating early-stage ovarian cancer or tumours that are limited in size and have not spread to the abdominal cavity. | The robotic system provides surgeons with a magnified three-dimensional view and highly precise instrument control, allowing for greater surgical precision, less damage to surrounding tissue, smaller incisions, and faster recovery. | However, it is not suitable for all stages of the disease, particularly when the cancer has spread to multiple sites within the abdominal cavity. |
| HIPEC | Treatment combines heated chemotherapy with surgery to target small cancer deposits within the abdominal cavity. | It may be suitable for patients with advanced ovarian cancer after the main tumour has been surgically removed. | The heated chemotherapy is designed to destroy cancer cells within the abdominal cavity while limiting exposure to the rest of the body, helping to reduce severe side effects such as hair loss, nausea, and vomiting. | This is a complex treatment that requires a thorough assessment of the patient’s overall health and suitability. |
| Niraparib | Oral medication can help delay cancer recurrence and prolong periods of remission. | It may also help control the disease after chemotherapy, particularly in some patients with advanced or recurrent ovarian cancer. | In some cases, it can help control the disease and prolong remission. | Blood tests, blood pressure, and side effects must be monitored as directed by your doctor. |
| ctDNA Liquid Biopsy | Advanced Genomic Profiling for precision treatment planning and cancer monitoring. | For cancer patients seeking precision therapy, and survivors concerned about recurrence. | High-precision detection that identifies risks before tumours develop, enabling personalised treatment design. | Requires specialist medical evaluation; costs vary based on individualised testing profiles. |
1. Robotic Surgery
What Is Robotic Surgery?
Robotic surgery is a minimally invasive surgical technique in which a surgeon controls robotic instruments through small incisions. It is particularly suitable for highly precise procedures in the narrow and deep areas of the female reproductive system, such as those for endometrial, cervical, and ovarian cancers.
Advantages of Robotic Surgery
- The robotic system provides greater stability and more precise instrument control than conventional laparoscopic surgery.
- During the procedure, the surgeon views a high-definition three-dimensional image, with up to 10–15× magnification, allowing clear visualisation of nerves and small blood vessels. This enables greater surgical precision in complex areas while reducing damage to surrounding tissues.
- Smaller incisions may lead to faster recovery compared with other surgical techniques.
- The risk of complications, such as wound infection or post-operative adhesions, may be reduced, allowing patients to proceed to further treatment more quickly.
Who Is Robotic Surgery Suitable For?
Robotic surgery may be suitable for some patients with early-stage ovarian cancer or tumours that are limited in size and have not spread extensively within the abdominal cavity.
However, if the disease is advanced, has spread to multiple sites within the abdominal cavity, or requires extensive tumour removal, the doctor may recommend a different surgical approach that is more appropriate.
2.HIPEC: Heated Chemotherapy Combined with Surgery for Some Cases of Advanced Ovarian Cancer
What Is HIPEC?
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a treatment in which heated chemotherapy is delivered directly into the abdominal cavity to treat advanced ovarian cancer. In general, surgeons first remove as much of the visible tumour as possible before considering HIPEC to treat any remaining microscopic cancer cells that cannot be seen with the naked eye.
Advantages of HIPEC
- HIPEC uses heated chemotherapy at a controlled temperature of 41°C to 43°C, which is considered the optimal range for destroying cancer cells while minimising damage to normal tissue.
- The heat helps dilate blood vessels, allowing the chemotherapy drug to penetrate tissues more effectively and increasing its effect within the targeted area.
- The chemotherapy is delivered directly into the abdominal cavity rather than through the bloodstream. This allows higher concentrations of the drug to be used where needed, although patients still require careful monitoring for potential side effects.
Who Is HIPEC Suitable For?
Doctors may consider HIPEC for some patients with advanced ovarian cancer or cancer that has spread within the abdominal cavity, where surgery to remove as much of the tumour as possible is considered appropriate.
However, HIPEC is always performed in combination with surgery. It is therefore regarded as a major and complex procedure with potential side effects. Before recommending this treatment, doctors will carefully consider several factors, including the stage and location of the disease, the patient’s overall health, the function of vital organs, fitness for major surgery, and the treatment goals for each individual patient.
3. Niraparib: Targeted Therapy for Maintenance Post-Chemotherapy
What is Niraparib?
Niraparib is an oral targeted therapy belonging to the class of PARP inhibitors. Oncologists may consider it as maintenance therapy for certain ovarian cancer patients following the completion of chemotherapy. Its primary goals are to control the disease, prolong remission, or delay recurrence in specific cases.
This class of drugs works by targeting and inhibiting the DNA repair mechanism within cancer cells. When cancer cells are unable to repair their DNA, they eventually shrink and die.
A specialist will determine suitability based on multiple factors, including cancer type, stage, response to chemotherapy, genetic or molecular test results, and the patient’s overall health. Patients prescribed Niraparib require ongoing clinical monitoring, including routine blood tests, blood pressure tracking, and side-effect assessments under medical supervision.
Who is Niraparib suitable for?
Niraparib may be appropriate for certain ovarian cancer patients after completing chemotherapy—particularly those with advanced-stage disease, those at high risk of recurrence, or where maintenance therapy is clinically indicated.
4. ctDNA Liquid Biopsy: Innovative Cancer Monitoring at the DNA Level
What is ctDNA Liquid Biopsy?
ctDNA Liquid Biopsy is an advanced Genomic Profiling innovation designed for precision cancer treatment planning and monitoring. Utilising Next-Generation Sequencing (NGS) technology, it provides an in-depth analysis of cancer gene mutations.
Key Benefits of ctDNA Liquid Biopsy
Non-Invasive Liquid Biopsy
The hallmark of ctDNA Liquid Biopsy is the use of a liquid biopsy (a simple blood test) to detect circulating tumour DNA (ctDNA) shedding from cancer cells into the bloodstream.
Detecting Ultra-Low Levels of Residual Cancer
Following surgical tumour removal or the completion of chemotherapy, oncologists use ctDNA Liquid Biopsy to check for any microscopic cancer cells remaining in the body—levels so minute that conventional CT scans, MRIs, or standard lab tests might completely miss them.
By scheduling periodic ctDNA Liquid Biopsy (subsequent tests), oncologists can proactively monitor patients. This allows them to detect potential recurrence at the molecular level—long before a physical tumour has time to form—enabling swift, early-stage intervention.
Who is ctDNA Liquid Biopsy suitable for?
ctDNA Liquid Biopsy is highly recommended for three primary groups of patients:
- Newly Diagnosed Patients Planning Treatment
By analysing cancer mutations at the DNA level, oncologists can precisely match patients with the most effective targeted therapies or immunotherapies tailored to their specific genetic profile. This highly personalised approach saves time and avoids the unnecessary costs of trial-and-error treatments. - Patients Post-Surgery or Post-Chemotherapy
ctDNA Liquid Biopsy screens for Minimal Residual Disease (MRD)—tiny traces of cancer cells left in the blood that are invisible to standard CT or MRI scans. This allows oncologists to plan preventive therapies or implement vigilant monitoring before the cancer has a chance to progress. - Cancer Survivors in Remission
For survivors concerned about recurrence, routine ctDNA Liquid Biopsy monitoring acts as an early warning system at the DNA level. Should the cancer begin to return, medical teams can detect and manage it at its absolute earliest, most treatable stage.
How Does Ovarian Cancer Treatment Differ at Each Stage?
| Disease Status | Treatment Approaches the Doctor May Consider | Treatment Goal |
| Early-stage disease or tumours of limited size | Surgery, including robotic surgery for suitable patients. | ฃTo remove the tumour or affected tissue and assess the stage of the disease. |
| Advanced disease or cancer that has spread within the abdominal cavity | Cytoreductive surgery (tumour debulking), chemotherapy, and HIPEC in selected patients. | To control the disease, reduce the tumour burden, and treat any remaining microscopic cancer cells. |
| After completion of chemotherapy, where the disease has responded to treatment | Ongoing monitoring or targeted therapy, such as niraparib, for suitable patients. | To help control the disease and reduce the risk of recurrence in some cases. |
| Recurrent disease or stage 4 disease | Personalised treatment based on test results and the patient’s overall health. | To control the disease, reduce symptoms, and maintain quality of life. |
Stage 4 ovarian cancer or metastatic disease often requires more complex treatment planning. Treatment goals may vary from case to case, so a specialist should assess the potential for disease control and develop an appropriate care plan.
Who Should Consult a Doctor About Ovarian Cancer Treatment?
- You have a family history of ovarian or breast cancer, or suspected genetic risk factors.
- You have been diagnosed with ovarian cancer and are seeking a treatment plan.
- You are currently considering which type of surgery is most suitable for you.
- You have advanced ovarian cancer or cancer that has spread to the abdominal cavity.
- You are undergoing chemotherapy and would like to discuss options for ongoing treatment.
- You have previously received treatment for ovarian cancer and would like an assessment of your follow-up care or risk of recurrence.
- You would like to discuss whether robotic surgery, HIPEC, Niraparib, and ctDNA Liquid Biopsy may be suitable for you.
- You would like a second opinion on your treatment plan.
The Difference in Ovarian Cancer Treatment at BNH Hospital
Ovarian cancer treatment requires assessment across multiple factors, including the stage of the disease, the location of the cancer, intra-abdominal metastases, pathology results, response to chemotherapy, overall health, and individual treatment goals. Therefore, managing ovarian cancer is complex and requires specialist expertise.
At BNH Hospital, we have over 128 years of experience in women’s healthcare. Our Women’s Health Centre, Gynaecology Centre, and Breast Health Centre provide holistic care, from screening and prevention to treatment and rehabilitation. Care is tailored to each individual’s needs by specialist physicians, supported by multidisciplinary teams, and incorporates innovative, high-standard treatments. This enables us to provide appropriate care for ovarian cancer patients at every stage of the disease.
In addition, BNH Hospital provides long-term follow-up care for women, including support for complications related to ovarian cancer, mental health concerns, fertility considerations, and concerns regarding family members. We also have expertise in genetic testing for risk assessment.
Interested in Ovarian Cancer Screening and Treatment at BNH Hospital?
The cost of ovarian cancer screening and treatment depends on the selected treatment options. Each patient’s medical needs are assessed individually based on factors such as diagnostic methods, disease stage, surgical plan, chemotherapy, consideration of HIPEC, targeted therapy such as niraparib, and the follow-up period after treatment.
Those interested can consult the BNH Women’s Health Centre team to arrange a consultation with a gynaecological oncologist, receive recommendations for suitable ovarian cancer screening packages, or assess appropriate treatment options before making a decision: Read More
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Regular Price
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Special Price
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5,450 Baht
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2,990 Baht
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Transvaginal Ultrasound Package
A uterine and ovarian ultrasound uses high-frequency sound waves to accurately diagnose the characteristics of the uterus, uterine fibroids, endometrial lining, and the presence of normal or abnormal ovaries. This internal scan allows the probe to be positioned closer to the uterus and ovaries than an abdominal scan, providing clearer images on the monitor. There’s also no need to wait or hold your urine before this examination.
Examinations
- Pelvic Examination by an Obstetric and Gynaecologist
- Transvaginal Ultrasound
Terms and Conditions
- All packages are inclusive of doctor’s fee, medical supplies, and hospital and nursing services fee.
- Expenses for additional consultation, investigation, or treatment other than the package are not included.
- All packages are transferable
- Please make an appointment at least 2 days prior to using the services via BNH Cares at LINE @BNHhospital or contact our staff for assistance at LINE @Mbrace
- Services are available at the Women’s Health Centre, 4th floor, zone A, BNH Hospital. Monday – Sunday at 7 am. – 7 pm.
- For more information, please contact the Women’s Health Centre, BNH Hospital at 02-022-0788 and 02-022-0850
- Services valid until15th September 2026.
Preparation
- It is recommended to undergo the examination at least 3 days after your period has ended.
- Before the examination, you should not douche or use vaginal suppositories for at least 2 days.
- Avoid sexual intercourse for at least 1 day before the examination.
- Please empty your bladder before the examination.
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Wear comfortable, loose-fitting clothing.
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Regular Price
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Special Price
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25,000 Baht
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19,900 Baht
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Essential 90-Gene Expanded Panel (ENCODE)
This test is designed to assess cancer risks that may be associated with hereditary factors, such as breast cancer, ovarian cancer, colorectal cancer, prostate cancer, pancreatic cancer, and certain other cancers that may be linked to family history.
The results can help doctors use genetic information as part of a comprehensive risk assessment, plan preventive screening, and provide more personalized health recommendations. However, genetic testing is not a cancer diagnosis. If no genetic abnormality is found, it does not mean that there is no risk of developing cancer in the future.
Examinations
- Essential 90-Gene Expanded Panel (ENCODE)
Terms and Conditions
- All packages are inclusive of doctor’s fee, medical supplies, and hospital and nursing services fee.
- Expenses for additional consultation, investigation, or treatment other than the package are not included.
- All packages are transferable
- Please make an appointment at least 2 days prior to using the services via BNH Cares at LINE @BNHhospital or contact our staff for assistance at LINE @Mbrace
- Services are available at the Women’s Health Centre, 4th floor, zone A, BNH Hospital. Monday – Sunday at 7 am. – 7 pm.
- For more information, please contact the Women’s Health Centre, BNH Hospital at 02-022-0788 and 02-022-0850
- Services valid until15th September 2026.
Preparation
- No fasting is required before the test.
Frequently Asked Questions
Q : Is ovarian cancer curable?
A : The possibility of curing or controlling ovarian cancer depends on several factors, including the type of cancer, stage of the disease, extent of spread, response to treatment, and the individual’s overall health. Each case should be assessed individually by a specialist.
Q : What are the treatments for early-stage ovarian cancer?
A : For early-stage ovarian cancer, surgery is usually the primary treatment option. In some cases, robotic surgery may be considered if the tumour is small and suitable for minimally invasive surgery. The most appropriate approach depends on the type of cancer, stage of disease, and the doctor’s assessment.
Q : Is there a chance of recovery from stage 4 ovarian cancer?
A : Stage 4 ovarian cancer is a complex condition that requires comprehensive treatment. Treatment goals may include controlling the disease, reducing symptoms, prolonging periods of remission, and maintaining quality of life. Some patients may respond well to treatment, but each case requires individual assessment by a specialist.
Q : What is HIPEC and how does it differ from conventional chemotherapy?
A : HIPEC is a treatment that involves administering heated chemotherapy directly into the abdominal cavity in combination with surgery. It aims to target small cancer cells that may remain after surgery. Unlike conventional chemotherapy, which is usually delivered through the bloodstream, HIPEC delivers chemotherapy directly within the abdominal cavity. As a result, exposure to the rest of the body may be reduced. However, HIPEC is a complex treatment and its suitability must be assessed by a specialist.
Q : What is niraparib?
A : Niraparib is an oral targeted therapy in the PARP inhibitor class. Doctors may consider using it as maintenance treatment after chemotherapy for some patients with ovarian cancer to help control the disease and reduce the risk of recurrence. Its suitability depends on each individual’s condition.
Q : How can I find out if I have ovarian cancer?
A : The symptoms of ovarian cancer are not always obvious. Patients may experience bloating, abdominal discomfort, lower abdominal pain, feeling full quickly, or frequent urination. If these symptoms persist, you should consult a doctor for evaluation, which may include a pelvic examination, ultrasound, blood tests, or other tests as considered appropriate.
Symptoms and Warning Signs of Ovarian Cancer: Read more
Q : Who is at risk for ovarian cancer?
A :Those who may have a higher risk include individuals with a family history of ovarian or breast cancer, certain genetic predispositions, or specific health factors. It is important to consult a doctor to assess individual risk.
Risk Groups for Ovarian Cancer: Read more
Q : What is a normal ovarian cancer marker?
A : The term “ovarian cancer marker” usually refers to a tumour marker such as CA-125. Many laboratories use a value below 35 U/mL as a general reference range; however, normal values may vary between laboratories. CA-125 alone cannot diagnose ovarian cancer, and results should always be interpreted together with a doctor’s assessment.
More Information
What Is Ovarian Cancer and How Does It Occur?
Understanding the basics of ovarian cancer, including its causes and how the disease develops: Read More
Symptoms and Warning Signs of Ovarian Cancer
Learn about symptoms that should not be ignored, such as bloating and lower abdominal pain: Read More
Risk Groups for Ovarian Cancer
An initial assessment of risk factors, including family history, age, and genetic risk: Readmore
Summary: Ovarian Cancer and Treatment Innovations
- Ovarian cancer requires comprehensive treatment planning because each patient may have different disease characteristics, stages of disease, patterns of spread, overall health conditions, and responses to treatment.
- New innovations in ovarian cancer treatment include robotic surgery, HIPEC, Niraparib, and ctDNA Liquid Biopsy Each plays a different role in ovarian cancer care, ranging from surgery for early-stage disease and management of advanced cancer that has spread within the abdominal cavity to helping reduce the risk of recurrence after chemotherapy.
- Doctors may consider combining several treatment approaches for ovarian cancer, including surgery, chemotherapy, targeted therapy, or other therapies, depending on each patient’s individual needs.
Consult a specialist in gynaecologic cancer.
Make an appointment or contact us for more information via LINE @BNHhospital
Gynaecology Centre, 4th Floor, Zone A, BNH Hospital
